Congress Programme: Thursday 29 June

Programme Thursday 29 June 2017



Registration opens

10:00 – 10:05

Room 217

Opening words on behalf of the Netherlands Heart Institute

Prof. dr. S. Heymans, chair of the programme committee

10:05 – 12:00

Room 217

Plenary programme

Key note lecture: “Better together: bridging the gap between science and the private sector” Jan Kimpen, (Philips Medical)


“Better together: 45 years of successful cooperation” Pieter Doevendans (Netherlands Heart Institute)


“Better together: patients working with scientists” Pieter Glijnis (chair foundation PLN)


Round table “Success through cooperation” chaired by Karin Hommen

  1. Arend Mosterd (WCN)
  2. Floris Italianer (Dutch Heart Foundation)
  3. Jolien Roos-Hesselink (ErasmusMC)
  4. Dirk Jan Duncker (Netherlands Heart Institute and Dutch Cardiovascular Alliance)
  5. Jan Kimpen (Philips)
  6. Jolanda van der Velden (VUmc)
  7. Daphne Bloemkolk (De Hart&Vaatgroep)


Highlights of the latest results of scientific research


This plenary session will be held in Dutch

12:00 – 13:00


Lunch break & Posters

13:00 – 15:00

Room 217

PHAEDRA & eDETECT: “From Prediction to Prevention of pulmonary arterial hypertension”

Chairs: Liza Botros (VUmc) and Jurjan Aman (VUmc)

Key note lecture: “Understanding pulmonary arterial hypertension through genetics” Nick Morell, Cambridge UK

  1. “From carrier to patient: the patients experience” Ellis Ribbens (chair of the patient advisory board VUmc)
  2. “From insight to treatment” Peter ten Dijke (LUMC)
  3. “Early recognition of hereditary PAH:  lessons from the eDETECT study” Peter van Tintelen (AMC)

Debate “Shaping the future of hereditary PAH”



13:00 – 15:00

Room 210


Chairs: Connie Bezzina (AMC) and Jeroen Bakkers (Hubrecht)

Key note lecture: “Adhesion-excitability coupling and the arrhythmia-cardiomyopathy spectrum” Mario Delmar, New York University, New York

  1. “DOSIS: Impaired energetics as cause of arrhythmias” Diederik Kuster (VUMC)
  2. “PREDICT: TNNI3K: From the lab to the clinic and back” Elisabeth Lodder (AMC)
  3. “PREDICT: Genetics and arrhythmogenic cardiomyopathy”, Edgar Hoorntje (Netherlands Heart Institute)
  4. “CONCOR: Genetic studies in Transposition of the Great Arteries (TGA)”, Doris Milosavljevic (AMC)

13:00 – 15:00

Room 218

The position of HUSTCARE in regenerative medicine

Chairs: Liangxue Lai (Guangzhou Institute of Biomedicine and Health) and Vincent Christoffels (AMC)

  1. “cardiac regeneration after HustCare” Pieter Doevendans (Netherlands Heart Institute)
  2. “Interventional MRI for cardiac regeneration” Steven Chamuleau (UMCU)
  3. “Looking back to think ahead; using old trial data for new insights” Peter-Paul Zwetsloot (UMCU)
  4. “Mapping proliferative cells and their progeny in damaged murine hearts” Kai Kretzschmar (Hubrecht Institute)
  5. “Proliferating adult cardiomyocytes in the regenerating heart resemble embryonic cardiomyocytes and have a distinct metabolic phenotype” Fabian Kruse (Hubrecht Institute)

13:00 – 15:00

Room 219


Chairs: Inge van den Munckhof (RadboudUMC) and Cornelia van Duijn (ErasmusMC)

Key note lecture: “Causality or not causality regarding involvement of gutmicrobiota in human cardiometabolism; that is the question!” Max Nieuwdorp, (AMC)

  1. “Host and Environmental Factors Influencing Individual Human Cytokine Responses” Rob ter Horst (RadboudUMC)
  2. “The effect of host genome and microbiome on the level of metabolites and proteins related to CVD: a population-based study” Alexander Kurilshikov (UMCG)
  3. “Microbiota dysbiosis augments atherosclerosis in LDLR KO mice” Debby Koonen (UMCG)
  4. “The effect of the gut microbiota on non-alcoholic fatty liver disease” Aafke Janssen (Wageningen University)

15:30 – 17:30

Room 217


Chairs: Johan Kuiper (LACDR) and Jan Albert Kuivenhoven (UMCG)

  1. “Overview of target finding in GENIUS” Johan Kuiper (LACDR)
  2. “Brown fat activation and atherosclerosis” Geerte Hoeke (LUMC)
  3. “LRP1 and atherosclerosis” Federico Oldoni (UMCG)
  4. “Monocyte activation and atherosclerosis” Sophie Bernelot-Moens (AMC)

15:30 – 17:30

Room 210


Chairs: Paula da Costa Martins (MUMC+) and Dirk Jan Duncker (Netherlands Heart Institute)

Key note lecture: “Novel sequencing technologies to identify new therapeutic candidates for heart failure” Eva van Rooij (Hubrecht Institute)

  1. “Mechanisms and therapeutic concepts in RBM20 induced heart failure” Esther Creemers (AMC)
  2. “RNA approaches to therapy-resistant heart failure” Leon de Windt (MUMC+)
  3. “Allelic imbalance affects disease severity in long QT syndrome type 1” Anke Tijsen (AMC)
  4. “New avenues in HFpEF treatment: a translational perspective” Ward Heggermont (KU Leuven)

15:30 – 17:30

Room 218

PHAEDRA: “Finding new solutions for pulmonary arterial hypertension”

Chairs: Daphne Merkus (Erasmus MC) & Babu Kurakula (postdoc LUMC)

Key note lecture: “The deadly vicious circle between pulmonary vascular remodelling and right heart failure” Anton Vonk Noordegraaf, (VUmc)

  1. “What can we learn from animals” Beatrijs Bartelds (ErasmusMC)
  2. “From animals to cells” Marie Jose Goumans (LUMC)
  3. “Testing a new drug in rare patients: a personal approach” Harm Jan Bogaard (VUmc)
  4. “don't forget the right ventricle” Frances Handoko - De Man (VUmc)

15:30 – 17:30

Room 219

Hands-on data management

Chairs: the Durrer Center for cardiovascular research together with TraIT and BBMRI

After a plenary introduction, participants follow mini-workshops to gain hands-on experience on datamanagement tools. Experts from Netherlands Heart Institute/Durrer Center, TraIT and BBMRI will introduce datamanagement tools to give an impression of what is already possible in the Netherlands in end-to-end biomedical translational data management. The following short hands-on sessions will be available:

-          Clinical data (REDCap)

-          Biomedical imaging (XNAT/NBIA)

-          Catalogue (Molgenis)

-          Biobanking (OpenSpecimen)

Please bring your own laptop

17:30 – 18:30


Drinks & Posters

18:30 – 20:30



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With the generous support of: